nifedipine will increase the amount or effect of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Check Intently (one)crofelemer improves levels of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Crofelemer has the opportunity to inhibit CYP3A4 at concentrations env